INHIBITION OF INTEGRIN alpha V beta 3 IMPROVES REXINOID ANTITUMORAL ACTION ON CUTANEOUS T CELL LYMPHOMA (CTCL).

REVUELTA M.V.; PHILLIP J.; MAGRO C.; CERCHIETTI L; CAYROL, FLORENCIA; PAULAZO M.A.; DIAZ FLAQUÉ C.; CREMASCHI G.A.; DEBERNARDI M.; ZAMPONI N.; RUAN J.

Barcelona

Congreso; 4th WorldCongress of Cutaneous Lymphoma; 2020

The effect of cilengitide on the efficacy of BEX is currently being analyzed in murine CTCL models. The poster was concluded by stating that these data indicate that, even in the present of TH replacement therapy, inhibition of the integrin αVβ3 improves the efficacy of bexarotene in CTCL.