BIOMED   24552
INSTITUTO DE INVESTIGACIONES BIOMEDICAS
Unidad Ejecutora - UE
artículos
Título:
Ghrelin and its interactions with growth hormone, leptin and orexins: Implications for the sleepewake cycle and metabolism
Autor/es:
GARCIA-GARCIA F; JUAREZ-AGUILAR E; SANTIAGO-GARCIA J; CARDINALI DP
Revista:
SLEEP MEDICINE REVIEWS
Editorial:
W B SAUNDERS CO LTD
Referencias:
Lugar: Londres; Año: 2014 vol. 18 p. 89 - 97
ISSN:
1087-0792
Resumen:
Several studies have shown that ghrelin
administration promotes wakefulness in rodents, while in human males it induces
sleep but has no effect in women. Ghrelin also plays an important role in
metabolism and appetite regulation, and as described in this review may
participate in the energy balance during sleep. In this review, we summarize
some of the effects induced by ghrelin administration on the sleep-wake cycle
in relation to the effects of other hormones, such as growth hormone, leptin,
and orexin. Finally we discuss the relationship between sleep deprivation,
obesity and ghrelin secretion pattern