Adhesion of blood platelets in TiO2 coatings

JONATHAN M. SCHUSTER; MARIA LAURA VERA; MARGARITA E. LACZESKI; CARLOS E. SCHVEZOV; MARIO R. ROSENBERGER

Orlando

Simposio; Biological Materials Science Symposium; 2015

TMS

Hemocompatibility is a requirement searched in materials used as prosthesis in contact with blood. No standard method were established to measure the hemocompatibility. However, it is know that the adsorption of proteins from blood is the initial stage in the interaction between material and blood; and, this process determine the way in that the blood platelets will adhere and activate, which would produce the blood coagulation. On the other hand, the TiO2 is a material extensively used in prosthesis due to the good response observed in contact with living tissue.In this work, the in vitro adhesion of platelets on coating of TiO2 are evaluated. The coating were performed by anodic oxidation using voltage ranged from 10 to 70 V, in sulphuric acid, followed by heat treatments. The platelets were observed by optical microscope and the results indicate that the coating synthesized at lower voltage shown lower adhesion.