Empirical demonstration of hybrid chromosomal races in house mice

THADSIN PANITHANARAK; MABEL D. GIMÉNEZ; JEREMY B. SEARLE; HEIDI C. HAUFFE

EVOLUTION

WILEY-BLACKWELL PUBLISHING, INC

Lugar: Londres; Año: 2016 vol. 70 p. 1651 - 1658

0014-3820

<!-- /* Font Definitions */@font-face{font-family:Cambria;panose-1:2 4 5 3 5 4 6 3 2 4;mso-font-charset:0;mso-generic-font-family:auto;mso-font-pitch:variable;mso-font-signature:3 0 0 0 1 0;} /* Style Definitions */p.MsoNormal, li.MsoNormal, div.MsoNormal{mso-style-parent:"";margin:0cm;margin-bottom:.0001pt;mso-pagination:widow-orphan;font-size:12.0pt;font-family:"Times New Roman";mso-ascii-font-family:Cambria;mso-ascii-theme-font:minor-latin;mso-fareast-font-family:Cambria;mso-fareast-theme-font:minor-latin;mso-hansi-font-family:Cambria;mso-hansi-theme-font:minor-latin;mso-bidi-font-family:"Times New Roman";mso-bidi-theme-font:minor-bidi;}@page Section1{size:612.0pt 792.0pt;margin:72.0pt 90.0pt 72.0pt 90.0pt;mso-header-margin:36.0pt;mso-footer-margin:36.0pt;mso-paper-source:0;}div.Section1{page:Section1;}-->Western house mice<!-- /* Font Definitions */@font-face{font-family:Cambria;panose-1:2 4 5 3 5 4 6 3 2 4;mso-font-charset:0;mso-generic-font-family:auto;mso-font-pitch:variable;mso-font-signature:3 0 0 0 1 0;} /* Style Definitions */p.MsoNormal, li.MsoNormal, div.MsoNormal{mso-style-parent:"";margin:0cm;margin-bottom:.0001pt;mso-pagination:widow-orphan;font-size:12.0pt;font-family:"Times New Roman";mso-ascii-font-family:Cambria;mso-fareast-font-family:Cambria;mso-hansi-font-family:Cambria;mso-bidi-font-family:"Times New Roman";}@page Section1{size:612.0pt 792.0pt;margin:72.0pt 90.0pt 72.0pt 90.0pt;mso-header-margin:36.0pt;mso-footer-margin:36.0pt;mso-paper-source:0;}div.Section1{page:Section1;}-->(Mus musculus domesticus)and common shrews (Sorex araneus) are importantmodels for study of chromosomal speciation. Both had ancestral karyotypesconsisting of telocentric chromosomes, and each is subdivided into numerouschromosomal races many of which have resulted from fixation of new mutations(Robertsonian fusions and whole-arm reciprocal translocations). However, somechromosomal races in both species may alternatively have originated throughhybridization, with particular homozygous recombinant products reachingfixation. Here, we demonstrate the process of generation of hybrid chromosomalraces for the first time in either species using molecular markers. Analysis ofcentromeric microsatellite markers show that the Mid Valtellina (IMVA) andUpper Valtellina (IUVA) chromosomal races of the house mouse are recombinantproducts of hybridization of the Lower Valtellina (ILVA) and Poschiavo (CHPO)chromosomal races, supporting earlier theoretical analysis. IMVA and IUVAoccupy a small area of the Italian Alps where ILVA makes contact with CHPO.IUVA and CHPO have previously been shown to be reproductively isolated in onevillage, emphasizing that hybrid chromosomal races in small mammals, as inplants, have the potential to be part of the speciation process.