CIFICEN   24414
CENTRO DE INVESTIGACIONES EN FISICA E INGENIERIA DEL CENTRO DE LA PROVINCIA DE BUENOS AIRES
Unidad Ejecutora - UE
congresos y reuniones científicas
Título:
NIR Diffuse Optical Imaging of Tissue-Like Phantoms With Immerse Inhomogeneities
Autor/es:
WAKS SERRA, MARÍA VICTORIA
Lugar:
Buenos Aires
Reunión:
Congreso; XVII Giambiagi Winter School; 2015
Institución organizadora:
Departamento de Física Universidad de Buenos Aires
Resumen:
In the latest years, interest has increase towards tissue imaging using NIR (Near Infrarred) light. Light interacts with biological tissues by absorption and scattering. For these tissues, in the NIR region, scattering is highly dominating over absorption, thus, light interacts multiple times before exiting the medium. It is known that lesions can be distinguished from healthy tissue by their different optical parameters. Besides, the NIR radiation is completely harmless, allowing its frequent utilization without the effects of ionizing radiation. This imaging technique may be complemented with the use of fluorescent markers, like ICG (Indocyanine green), whose pharmacokinetics is different in healthy tissues than in malignant lesions.I present here an overview of the work in progress, related to my PhD thesis, that focus on the localizaton in 3D and characterization of tumor-like inclusions embedded in turbid media. For this, purpose, I analyze the light emerging from the medium at different wavelengths, in the so called diffuse transmittance geometry using both, absorption and fluorescence images. The study is performed over phantoms, that are constructions emulating biological tissues (in this case, breast tissue), fabricated with distilled water, milk, ink and ICG. Furthermore I also made a research about the absorbent components. The inclusions employed are built with a higher absorption coefficient and higher ICG concentration, to represent breast tumors. A theoretical model is discussed and experimental result are presented.