CENTRO DE INVESTIGACIONES EN FISICA E INGENIERIA DEL CENTRO DE LA PROVINCIA DE BUENOS AIRES
Unidad Ejecutora - UE
Diffuse reflectance optical topography: location of inclusions in 3D and detectability limits
N. CARBONE; G. BAEZ; H. GARCIA; M. V. WAKS SERRA; H. O. DI ROCCO; D. I. IRIARTE; J. A. POMARICO; D. GROSENICK; R. MACDONALD
Biomedical Optics Express
Optical Society of America
Lugar: Washington; Año: 2014 vol. 5 p. 1336 - 1336
In the present contribution we investigate the images of CW diffusely reflected light for a point-like source, registered by a CCD camera imaging a turbid medium containing an absorbing lesion. We show that detection of μa variations (absorption anomalies) is achieved if images are normalized to background intensity. A theoretical analysis based on the diffusion approximation is presented to investigate the sensitivity and the limitations of our proposal and a novel procedure to find the location of the inclusions in 3D is given and tested. An analysis of the noise and its influence on the detection capabilities of our proposal is provided. Experimental results on phantoms are also given, supporting the proposed approach.