IMPAM 23988
INSTITUTO DE INVESTIGACIONES EN MICROBIOLOGIA Y PARASITOLOGIA MEDICA
Unidad Ejecutora - UE
artículos
Título:
A comprehensive bioinformatic analysis of hepatitis D virus full-length genomes
Autor/es:
BIGLIONE, M.; MATHET, V.L.; BIGLIONE, M.; MATHET, V.L.; CERRUDO, C.S.; GHIRINGHELLI, P.D.; CERRUDO, C.S.; GHIRINGHELLI, P.D.; DELFINO, C.M.; OUBIÑA, J.R.; DELFINO, C.M.; OUBIÑA, J.R.
Revista:
JOURNAL OF VIRAL HEPATITIS.
Editorial:
WILEY-BLACKWELL PUBLISHING, INC
Referencias:
Año: 2018 vol. 25 p. 860 - 869
ISSN:
1352-0504
Resumen:
In association with hepatitis B virus (HBV), hepatitis delta virus (HDV) is a subviral agent that may promote severe acute and chronic forms of liver disease. Based on the percentage of nucleotide identity of the genome, HDV was initially classified into three genotypes. However, since 2006, the original classification has been further expanded into eight clades/genotypes. The intergenotype divergence may be as high as 35%-40% over the entire RNA genome, whereas sequence heterogeneity among the isolates of a given genotype is
