IMPAM   23988
INSTITUTO DE INVESTIGACIONES EN MICROBIOLOGIA Y PARASITOLOGIA MEDICA
Unidad Ejecutora - UE
artículos
Título:
Polyclonal dissemination of KPC-2 in Serratia marcescens, including a clone with epidemic behaviour in the nosocomial niche
Autor/es:
RODRIGUEZ C; BRENGI S; CÁCERES MA; MOCHI S; VIÑAS MR; MERLETTI G; RAYA R; CENTRON D
Revista:
INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS
Editorial:
ELSEVIER SCIENCE BV
Referencias:
Lugar: Amsterdam; Año: 2017 vol. 49 p. 657 - 657
ISSN:
0924-8579
Resumen:
Serratia marcescens is a nosocomial pathogen frequently isolatedfrom outbreaks with highmorbidity andmortality [1?3]. Several nosocomialoutbreaks have been described caused by the dispersion ofepidemic clones carrying class 1 integrons [1?3], some of which alsoharbour Klebsiella pneumoniae carbapenemase-2 (KPC-2) incarbapenem-resistant S. marcescens nosocomial isolates [3,4], renderingphenotypes of extreme antimicrobial resistance. Previously,we have identified multidrug-resistant (MDR) S. marcescens strainsbelonging to epidemic cluster IX circulating since 2002 in Argentiniannosocomial isolates [2]. This clusterwas susceptible to carbapenemsand harboured class 1 integrons. Later, a significant increase in thefrequency of carbapenem-resistant S. marcescens nosocomial isolates(19.5/11.9 absolute/expected annual frequency) was identifiedin a hospital of northern Argentina (H1) between 2013 and 2014.
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