IBIMOL   23987
INSTITUTO DE BIOQUIMICA Y MEDICINA MOLECULAR PROFESOR ALBERTO BOVERIS
Unidad Ejecutora - UE
libros
Título:
Biflavonoids: Occurence, Structural Features & Bioactivity
Autor/es:
MERCADER, ANDREW G.; POMILIO, ALICIA, B.
Editorial:
Nova Science Publishers
Referencias:
Lugar: Nueva York; Año: 2012 p. 241
ISSN:
978-1-62100-354-0
Resumen:
Biflavonoids comprise a group of the flavonoid family that possesses a variety of structures, and biological activities of high relevance, such as anticancer, antibacterial, antifungal, antiviral, anti-inflammatory, antinociceptive, antioxidant, vasodilator, anticlotting, among others, regardless of the bioactivity of each monomer unit. The chemistry of biflavonoids is very important in many fields of research, especially because these compounds are structurally different bioactive molecules with potential for biomedical application. This book aims to highlight the structural biflavonoid variability, rearrangements, and different stereochemistry through about 470 structures distributed in some species of Angiosperms (monocots and dicots), Gymnosperms, ferns (Pteridophyta), and mosses (Bryophyta). Their distribution is shown to provide the latest picture of their natural sources, biological activities, and traditional uses. Chemical structures include simple dimers, complex biflavonoids, rearranged biflavonoids, natural Diels-Alder type adducts, and spirobiflavonoids. The most important general characteristics, structures and nomenclature of the biflavonoids have been covered, and biological activities are carefully displayed. The structural aspects of the biflavonoids are shown in a detailed list of figures, thus providing an overview of their structural features. The current status and future prospects of the structure-activity studies of these compounds are also discussed.