High-fat diet and (‒)-epicatechin supplementation: comparative effects on cardiac and skeletal-muscle.

BARBARA PIOTRKOWSKI; LAURA VALDEZ; IVANA RUKAVINA MIKUSIC; CESAR G FRAGA; LAURA FISCHERMAN; MÓNICA GALLEANO

Ferrara

Congreso; REDOX HOMEOSTASIS: FROM SIGNALLING TO DAMAGE; 2019

SFRR-E

In this work, we studied EC effects on cardiac and skeletal muscle mitochondrial function from high-fat fed mice. Male mice were fed for 15 w with diets containing 10% total calories from fat (C), 60% total calories from fat (HF), C diet added with EC to provide 20 mg EC/kg body (CE), and HF diet plus same amount of EC (HFE). Mitochondrial respiratory complexes I-III, II-III, and IV activities were higher in cardiac (27%, 24% and 27%) and skeletal muscle (28%, 43% and 43% respectively; p