IBIMOL   23987
INSTITUTO DE BIOQUIMICA Y MEDICINA MOLECULAR PROFESOR ALBERTO BOVERIS
Unidad Ejecutora - UE
capítulos de libros
Título:
Selection of an optimal set of descriptors: use of the Enhanced Replacement Method
Autor/es:
MERCADER, ANDREW G.
Libro:
QSPR-QSAR STUDIES ON DESIRED PROPOERTIES FOR DRUG DESIGN
Editorial:
Signpost Design
Referencias:
Lugar: India; Año: 2009;
Resumen:
The Enhanced Replacement Method (ERM) is a search algorithm that selects an optimal group of descriptors from a much greater set in the construction of linear QSAR/QSPR models. This algorithm has shown many superior attributes that will be presented in this chapter. Successful applications will be shown to give a better general picture. Additionally an innovative methodology to determine the optimal number of parameters using the ERM will be presented.