IBIMOL 23987
INSTITUTO DE BIOQUIMICA Y MEDICINA MOLECULAR PROFESOR ALBERTO BOVERIS
Unidad Ejecutora - UE
artículos
Título:
Forms of Iron Binding in the Cells and the Chemical Features of Chelation Therapy
Autor/es:
PUNTARULO S; GALLEANO M
Revista:
MINI-REVIEWS IN MEDICINAL CHEMISTRY
Editorial:
Bentham Science Publishers
Referencias:
Lugar: Burlington; Año: 2009 vol. 9 p. 1136 - 1146
ISSN:
1389-5575
Resumen:
Iron is essential for human life, however it can be toxic through Fe ability to generate oxygen-derived radicals. This work reviews the main features of Fe binding in the cell and its association to these processes. The chemical nature of the Fe extracted by chelation therapy in pathophysiological situations is also analyzed.
