IBIMOL 23987
INSTITUTO DE BIOQUIMICA Y MEDICINA MOLECULAR PROFESOR ALBERTO BOVERIS
Unidad Ejecutora - UE
artículos
Título:
Dietary (-)-epicatechin affects NF-kB activation and NADPH-oxidases in the kidney cortex of high fructose-fed rats
Autor/es:
FRAGA, CG; PRINCE, PD; GALLEANO, M; RODRÍGUEZ LANZI C
Revista:
Food & Function
Editorial:
Royal Society of Chemistry
Referencias:
Año: 2019 vol. 10 p. 26 - 32
ISSN:
2042-6496
Resumen:
Inflammation involves the activation of redox-sensitive transcription factors, e.g. nuclear factor kB (NF-kB). Administration of (-)-epicatechin to high fructose-fed rats prevented NF-kB activation, and up-regulation of the NADPH oxidase 4 (NOX4) in kidney cortex. These results add mechanistic insight into the action of (-)-epicatechin diminishing inflammatory responses.
