Antioxidant status in the aqueous humour of patients with glaucoma associated with exfoliation syndrome.

FERREIRA S,; LERNER F; BRUNZINI R; EVELSON P; LLESUY S

EYE

NATURE PUBLISHING GROUP

Lugar: Inglaterra; Año: 2009 vol. 23 p. 1691 - 1697

0950-222X

PURPOSE: To establish the antioxidant status of the aqueous humour in glaucoma associated with exfoliation syndrome (XFG) and to compare it to primary open-angle glaucoma (POAG) and cataract patients. METHODS: Patients were diagnosed with POAG, XFG, or cataract (n=25 for each group). Total reactive antioxidant potential (TRAP) was measured by chemiluminescence. Ascorbic acid levels and the activities of catalase, glutathione peroxidase (GPx), and superoxide dismutase (SOD) were measured spectrophotometrically.ResultsTRAP value was lower in XFG (28+/-2 microM Trolox) than in POAG (55+/-8 microM Trolox; P