IBIMOL 23987
INSTITUTO DE BIOQUIMICA Y MEDICINA MOLECULAR PROFESOR ALBERTO BOVERIS
Unidad Ejecutora - UE
artículos
Título:
Redox regulation of inflammatory processes
Autor/es:
VALACCHI, GIUSEPPE; EVELSON, PABLO; RAHMAN, IRMAN; CERVELLATI, FRANCO
Revista:
INTERNATIONAL JOURNAL OF BIOCHEMISTRY AND CELLULAR BIOLOGY
Editorial:
PERGAMON-ELSEVIER SCIENCE LTD
Referencias:
Lugar: Amsterdam; Año: 2016 vol. 81 p. 234 - 235
ISSN:
1357-2725
Resumen:
Oxidative stress mediators such as Reactive Oxygen Species(ROS) and Reactive Nitrogen Species (RNS) can be considered double edge molecules, whenever their role in inflammatory pathways is considered. Indeed, if on one hand ROS/RNS are important inflam-matory effectors involved in the invading pathogens clearance andresolving the damage and inducing tissue repair; on the other hand,ROS/RNS can also be inflammatory initiators as a consequence ofoxidizing biomolecules such as lipids, proteins and DNA, leading to tissue damage and switching acute to chronic inflammation.
