IBIMOL   23987
INSTITUTO DE BIOQUIMICA Y MEDICINA MOLECULAR PROFESOR ALBERTO BOVERIS
Unidad Ejecutora - UE
artículos
Título:
2D- and 3D-QSAR studies of flavonoids, biflavones and chalcones: antiviral, antibacterial, antifungal, and antimycobacterial activities
Autor/es:
A. G. MERCADER; A. B. POMILIO
Revista:
Anti-Infective Agents (ex Anti-Infective Agents in Medicinal Chemistry)
Editorial:
Bentham Science Publishers
Referencias:
Lugar: Oak Park, IL; Año: 2012 vol. 10 p. 41 - 54
ISSN:
2211-3525
Resumen:
ABSTRACT: Flavonoids comprise a group of naturally occurring compounds that are known by their biological properties. Antiviral, antibacterial, antifungal, and antimycobacterial activities were analyzed. The results were discussed in terms of the bioactivity tested, and the structure-activity relationship (SAR), bidimensional (2D)- and three-dimensional (3D)- quantitative structure-activity relationship (QSAR) studies carried out on flavones, flavanones, chalcones, and some biflavonoids.