Comparative toxicity of oxygenated monoterpenoids in experimental hydroalcoholic lotions to permethrin-resistant adult head lice

P. GONZALEZ-AUDINO, M. I. PICOLLO, A. GALLARDO, A. TOLOZA, C. VASSENA AND G. MOUGABURE-CUETO

ARCHIVES OF DERMATOLOGICAL RESEARCH

SPRINGER

Año: 2011 p. 362 - 366

0340-3696

The use of botanical compounds such as essential oils has recently become the subject of great interest as a natural means of pest control because of their ovicidal, larvicidal, or adulticidal activity against various insect species including head lice. We tested and compared the efficacy of pure oxygenated monoterpenoids that are main ingredients of essential oils of good biological activity. We used pulegone and citral, components of Aloysia citrodora, and geraniol, citronellol, and linalool, components of Geranium geraniol, citronellol, and linalool, components of Geranium geraniol, citronellol, and linalool, components of Geranium geraniol, citronellol, and linalool, components of Geranium Aloysia citrodora, and geraniol, citronellol, and linalool, components of GeraniumGeranium sp. oil. We found that citronellol and geraniol showed the highest knockdown and mortality effect ([60%) on adults of both sexes (50:50%) and third-stage nymphs. Pulegone, linalool, and citral showed knockdown percentages between 42 and 55%, and mortality percentages between 47 and 53%. A simple linear regression analysis showed statistically significant relationships between the studied toxic effects and viscosity of the monoterpenoids (p0.05), but not with their partition coefficient (log P). their partition coefficient (log P). their partition coefficient (log P). their partition coefficient (log P). both sexes (50:50%) and third-stage nymphs. Pulegone, linalool, and citral showed knockdown percentages between 42 and 55%, and mortality percentages between 47 and 53%. A simple linear regression analysis showed statistically significant relationships between the studied toxic effects and viscosity of the monoterpenoids (p0.05), but not with their partition coefficient (log P). their partition coefficient (log P). their partition coefficient (log P). their partition coefficient (log P). both sexes (50:50%) and third-stage nymphs. Pulegone, linalool, and citral showed knockdown percentages between 42 and 55%, and mortality percentages between 47 and 53%. A simple linear regression analysis showed statistically significant relationships between the studied toxic effects and viscosity of the monoterpenoids (p0.05), but not with their partition coefficient (log P). their partition coefficient (log P). their partition coefficient (log P). their partition coefficient (log P). both sexes (50:50%) and third-stage nymphs. Pulegone, linalool, and citral showed knockdown percentages between 42 and 55%, and mortality percentages between 47 and 53%. A simple linear regression analysis showed statistically significant relationships between the studied toxic effects and viscosity of the monoterpenoids (p0.05), but not with their partition coefficient (log P). their partition coefficient (log P). their partition coefficient (log P). their partition coefficient (log P). [60%) on adults of both sexes (50:50%) and third-stage nymphs. Pulegone, linalool, and citral showed knockdown percentages between 42 and 55%, and mortality percentages between 47 and 53%. A simple linear regression analysis showed statistically significant relationships between the studied toxic effects and viscosity of the monoterpenoids (p0.05), but not with their partition coefficient (log P). their partition coefficient (log P). their partition coefficient (log P). their partition coefficient (log P). p0.05), but not with their partition coefficient (log P).P).