UNIDEF   23986
UNIDAD DE INVESTIGACION Y DESARROLLO ESTRATEGICO PARA LA DEFENSA
Unidad Ejecutora - UE
artículos
Título:
Susceptibility of Sylvatic Triatoma infestans From Andeans Valleys of
Autor/es:
ROCA ACEVEDO G; MOUGABURE CUETO G.; GERMANO M.; SANTO ORIHUELA P; ROJAZ CORTES M. ; NOIREAU F; PICOLLO M.I.; VASSENA C.
Revista:
JOURNAL OF MEDICAL ENTOMOLOGY
Editorial:
ENTOMOLOGICAL SOC AMER
Referencias:
Año: 2011 p. 825 - 835
ISSN:
0022-2585
Resumen:
ABSTRACT We describe the susceptibility to deltamethrin and Þpronil of four sylvatic Triatoma infestans populations from the Andean valleys of Bolivia. Fifty percent lethal doses were determined from topical application of insecticide on Þrst instars, and mortality was assessed after 24 h for deltamethrin and 48 h for Þpronil. In comparison with a reference strain from Argentina, the Bolivian populations showed deltamethrin 50 percent lethal dose ratios ranging from 1.9 to 17.4. In the case of Þpronil, aninsecticideneverusedfor control of T. infestans, the Bolivian populationsshowedevenhigher variation in toxic response, with relative susceptibilities ranging from 0.5 to 139.2. However, although the sylvatic T. infestans toxicological proÞles differfromeachotherandfromthoseofthedomiciliarypopulation studied in this work, there were no signiÞcant differences in the activities of P450 mono-oxygenases and pyrethroid esterases between the reference strain and the studied populations. studied in this work, there were no signiÞcant differences in the activities of P450 mono-oxygenases and pyrethroid esterases between the reference strain and the studied populations. variation in toxic response, with relative susceptibilities ranging from 0.5 to 139.2. However, although the sylvatic T. infestans toxicological proÞles differfromeachotherandfromthoseofthedomiciliarypopulation studied in this work, there were no signiÞcant differences in the activities of P450 mono-oxygenases and pyrethroid esterases between the reference strain and the studied populations. studied in this work, there were no signiÞcant differences in the activities of P450 mono-oxygenases and pyrethroid esterases between the reference strain and the studied populations. from topical application of insecticide on Þrst instars, and mortality was assessed after 24 h for deltamethrin and 48 h for Þpronil. In comparison with a reference strain from Argentina, the Bolivian populations showed deltamethrin 50 percent lethal dose ratios ranging from 1.9 to 17.4. In the case of Þpronil, aninsecticideneverusedfor control of T. infestans, the Bolivian populationsshowedevenhigher variation in toxic response, with relative susceptibilities ranging from 0.5 to 139.2. However, although the sylvatic T. infestans toxicological proÞles differfromeachotherandfromthoseofthedomiciliarypopulation studied in this work, there were no signiÞcant differences in the activities of P450 mono-oxygenases and pyrethroid esterases between the reference strain and the studied populations. studied in this work, there were no signiÞcant differences in the activities of P450 mono-oxygenases and pyrethroid esterases between the reference strain and the studied populations. variation in toxic response, with relative susceptibilities ranging from 0.5 to 139.2. However, although the sylvatic T. infestans toxicological proÞles differfromeachotherandfromthoseofthedomiciliarypopulation studied in this work, there were no signiÞcant differences in the activities of P450 mono-oxygenases and pyrethroid esterases between the reference strain and the studied populations. studied in this work, there were no signiÞcant differences in the activities of P450 mono-oxygenases and pyrethroid esterases between the reference strain and the studied populations. infestans populations from the Andean valleys of Bolivia. Fifty percent lethal doses were determined from topical application of insecticide on Þrst instars, and mortality was assessed after 24 h for deltamethrin and 48 h for Þpronil. In comparison with a reference strain from Argentina, the Bolivian populations showed deltamethrin 50 percent lethal dose ratios ranging from 1.9 to 17.4. In the case of Þpronil, aninsecticideneverusedfor control of T. infestans, the Bolivian populationsshowedevenhigher variation in toxic response, with relative susceptibilities ranging from 0.5 to 139.2. However, although the sylvatic T. infestans toxicological proÞles differfromeachotherandfromthoseofthedomiciliarypopulation studied in this work, there were no signiÞcant differences in the activities of P450 mono-oxygenases and pyrethroid esterases between the reference strain and the studied populations. studied in this work, there were no signiÞcant differences in the activities of P450 mono-oxygenases and pyrethroid esterases between the reference strain and the studied populations. variation in toxic response, with relative susceptibilities ranging from 0.5 to 139.2. However, although the sylvatic T. infestans toxicological proÞles differfromeachotherandfromthoseofthedomiciliarypopulation studied in this work, there were no signiÞcant differences in the activities of P450 mono-oxygenases and pyrethroid esterases between the reference strain and the studied populations. studied in this work, there were no signiÞcant differences in the activities of P450 mono-oxygenases and pyrethroid esterases between the reference strain and the studied populations. from topical application of insecticide on Þrst instars, and mortality was assessed after 24 h for deltamethrin and 48 h for Þpronil. In comparison with a reference strain from Argentina, the Bolivian populations showed deltamethrin 50 percent lethal dose ratios ranging from 1.9 to 17.4. In the case of Þpronil, aninsecticideneverusedfor control of T. infestans, the Bolivian populationsshowedevenhigher variation in toxic response, with relative susceptibilities ranging from 0.5 to 139.2. However, although the sylvatic T. infestans toxicological proÞles differfromeachotherandfromthoseofthedomiciliarypopulation studied in this work, there were no signiÞcant differences in the activities of P450 mono-oxygenases and pyrethroid esterases between the reference strain and the studied populations. studied in this work, there were no signiÞcant differences in the activities of P450 mono-oxygenases and pyrethroid esterases between the reference strain and the studied populations. variation in toxic response, with relative susceptibilities ranging from 0.5 to 139.2. However, although the sylvatic T. infestans toxicological proÞles differfromeachotherandfromthoseofthedomiciliarypopulation studied in this work, there were no signiÞcant differences in the activities of P450 mono-oxygenases and pyrethroid esterases between the reference strain and the studied populations. studied in this work, there were no signiÞcant differences in the activities of P450 mono-oxygenases and pyrethroid esterases between the reference strain and the studied populations. We describe the susceptibility to deltamethrin and Þpronil of four sylvatic Triatoma infestans populations from the Andean valleys of Bolivia. Fifty percent lethal doses were determined from topical application of insecticide on Þrst instars, and mortality was assessed after 24 h for deltamethrin and 48 h for Þpronil. In comparison with a reference strain from Argentina, the Bolivian populations showed deltamethrin 50 percent lethal dose ratios ranging from 1.9 to 17.4. In the case of Þpronil, aninsecticideneverusedfor control of T. infestans, the Bolivian populationsshowedevenhigher variation in toxic response, with relative susceptibilities ranging from 0.5 to 139.2. However, although the sylvatic T. infestans toxicological proÞles differfromeachotherandfromthoseofthedomiciliarypopulation studied in this work, there were no signiÞcant differences in the activities of P450 mono-oxygenases and pyrethroid esterases between the reference strain and the studied populations. studied in this work, there were no signiÞcant differences in the activities of P450 mono-oxygenases and pyrethroid esterases between the reference strain and the studied populations. variation in toxic response, with relative susceptibilities ranging from 0.5 to 139.2. However, although the sylvatic T. infestans toxicological proÞles differfromeachotherandfromthoseofthedomiciliarypopulation studied in this work, there were no signiÞcant differences in the activities of P450 mono-oxygenases and pyrethroid esterases between the reference strain and the studied populations. studied in this work, there were no signiÞcant differences in the activities of P450 mono-oxygenases and pyrethroid esterases between the reference strain and the studied populations. from topical application of insecticide on Þrst instars, and mortality was assessed after 24 h for deltamethrin and 48 h for Þpronil. In comparison with a reference strain from Argentina, the Bolivian populations showed deltamethrin 50 percent lethal dose ratios ranging from 1.9 to 17.4. In the case of Þpronil, aninsecticideneverusedfor control of T. infestans, the Bolivian populationsshowedevenhigher variation in toxic response, with relative susceptibilities ranging from 0.5 to 139.2. However, although the sylvatic T. infestans toxicological proÞles differfromeachotherandfromthoseofthedomiciliarypopulation studied in this work, there were no signiÞcant differences in the activities of P450 mono-oxygenases and pyrethroid esterases between the reference strain and the studied populations. studied in this work, there were no signiÞcant differences in the activities of P450 mono-oxygenases and pyrethroid esterases between the reference strain and the studied populations. variation in toxic response, with relative susceptibilities ranging from 0.5 to 139.2. However, although the sylvatic T. infestans toxicological proÞles differfromeachotherandfromthoseofthedomiciliarypopulation studied in this work, there were no signiÞcant differences in the activities of P450 mono-oxygenases and pyrethroid esterases between the reference strain and the studied populations. studied in this work, there were no signiÞcant differences in the activities of P450 mono-oxygenases and pyrethroid esterases between the reference strain and the studied populations. populations from the Andean valleys of Bolivia. Fifty percent lethal doses were determined from topical application of insecticide on Þrst instars, and mortality was assessed after 24 h for deltamethrin and 48 h for Þpronil. In comparison with a reference strain from Argentina, the Bolivian populations showed deltamethrin 50 percent lethal dose ratios ranging from 1.9 to 17.4. In the case of Þpronil, aninsecticideneverusedfor control of T. infestans, the Bolivian populationsshowedevenhigher variation in toxic response, with relative susceptibilities ranging from 0.5 to 139.2. However, although the sylvatic T. infestans toxicological proÞles differfromeachotherandfromthoseofthedomiciliarypopulation studied in this work, there were no signiÞcant differences in the activities of P450 mono-oxygenases and pyrethroid esterases between the reference strain and the studied populations. studied in this work, there were no signiÞcant differences in the activities of P450 mono-oxygenases and pyrethroid esterases between the reference strain and the studied populations. variation in toxic response, with relative susceptibilities ranging from 0.5 to 139.2. However, although the sylvatic T. infestans toxicological proÞles differfromeachotherandfromthoseofthedomiciliarypopulation studied in this work, there were no signiÞcant differences in the activities of P450 mono-oxygenases and pyrethroid esterases between the reference strain and the studied populations. studied in this work, there were no signiÞcant differences in the activities of P450 mono-oxygenases and pyrethroid esterases between the reference strain and the studied populations. T. infestans, the Bolivian populationsshowedevenhigher variation in toxic response, with relative susceptibilities ranging from 0.5 to 139.2. However, although the sylvatic T. infestans toxicological proÞles differfromeachotherandfromthoseofthedomiciliarypopulation studied in this work, there were no signiÞcant differences in the activities of P450 mono-oxygenases and pyrethroid esterases between the reference strain and the studied populations. studied in this work, there were no signiÞcant differences in the activities of P450 mono-oxygenases and pyrethroid esterases between the reference strain and the studied populations. T. infestans toxicological proÞles differfromeachotherandfromthoseofthedomiciliarypopulation studied in this work, there were no signiÞcant differences in the activities of P450 mono-oxygenases and pyrethroid esterases between the reference strain and the studied populations.