OXYTETRACYCLINE ADMINISTRATION TO SOWS DURING PERIPARTUM: RESIDUES IN COLOSTRUM AND IMPACT ON ZOOTECHNICAL PARAMETERS OF THE LITTER

DIEGUEZ, SUSANA NELLY; PÉREZ GAUDIO, DENISA SOLEDAD; SORACI, ALEJANDRO LUIS; MARTÍNEZ, GUADALUPE; ROMANELLI, AGUSTINA; FERNÁNDEZ PAGGI, MARÍA BELÉN; DECUNDO, JULIETA MARÍA; AMANTO, FABIÁN A.

Wroclaw

Congreso; 14th International Congress of the European Association for Veterinary Pharmacology and Toxicology; 2018

European Association for Veterinary Pharmacology and Toxicology (EAVPT) and the European College of Veterinary Pharmacology and Toxicology (ECVPT)

The aim of this study was to establish colostrum intake, estimate oxytetracicline (OTC) residues ingested by new born piglets and its impact on the litter´s zootechnical parameters after treatment of sows with OTC during peripartum.Farrow was induced with 1 mL PGF2α IM to 20 healthy, second farrowing sows at 114 days of gestation. Ten sows were used as control and ten received 3 doses of 6 mg/kg BW OTC being the first dose administered at the time of induction and then every 24 h. Born alive piglets were video recorded during 24 h (PPS, Pro Surveillence Sytem®) in order to calculate colostrum production and intake by sows and litters respectively using Deviller´s et al. equation. Total born piglets, born alive, vitality score at birth, number of weaned piglets at 21 d, presence of diarrhea, mortality during lactation, weight at birth, 1, 10 and 21 days were recorded. Colostrum samples were collected at standardized intervals and OTC residues were analyzed by HPLC-UV. OTC intake by the litter was estimated from residues concentration and colostrum intake calculation. Colostrum production was 3480.38 ± 359.98 and 3027.25 ± 247.25 g/sow (p>0.05) for control or treated sow respectively while colostrum intake was 270.61 ± 30.00 and 273.83 ± 21.63 g/kg BW (p>0.05) for piglets from control and treated sows respectively. Mean OTC concentration in colostrum was 0.48 ± 0.07 μg/mL. Estimated OTC intake with colostrum was 0.13 mg/kg BW. The piglets did not present diarrhoeas throughout the trial. No statistically significant differences were obtained in none of the zootechnical parameters studied between piglets from control or treated sows.