Impact of extra-label use of albendazole and fipronil in poultry

CEBALLOS LAURA; ALVAREZ LUIS; DOMÍNGUEZ PAULA; LANUSSE CARLOS; CANTÓN LUCILA; FARÍAS CRISTINA; MORENO LAURA

Kuala Lumpur

Conferencia; 26 International Conference of the World Association for the Advancement of Veterinary Parasitology; 2017

The World Association for the Advancement of Veterinary Parasitology

The increase of argentine poultry production in the last years is closely linked by the use of antiparasitic drugs in order to optimize this production, being the compounds available scarce. Albendazole (ABZ) and fipronil (FIP) are used extra-label for the control of nematode and external parasites, respectively. The goals of the study were: a) to evaluate the ABZ egg residues and its effect on the fertility and hatchability (Study-A); b) to investigate the FIP egg residues profiles after its extra-label administration to laying-hens (Study-B). Study-A: Forty eight (48) breeder hens were randomly divided into four groups and treated with ABZ at either 10, 40 or 80 mg/kg/day in feed over seven days, an untreated group was used as Control. Eggs were incubated under controlled conditions and fertility and hatchability were assessed. Study-B: Hens from a local farm were extralabel treated with FIP in feed. Eggs were collected for a 36 days post-treatment period. In Study-A, while fertility was not affected by ABZ, the hatchability values decreased inversely with the administered ABZ dose level. A statistically significant (P