CIVETAN 23983
CENTRO DE INVESTIGACION VETERINARIA DE TANDIL
Unidad Ejecutora - UE
artículos
Título:
The herbicide glyphosate is a weak inhibitor of acetylcholinesterase in rats
Autor/es:
LIFSCHITZ A.; LARSEN, K; LANUSSE C.; VIRKEL G.; LIFSCHITZ A.; LARSEN, K; VIRKEL G.; LANUSSE C.
Revista:
ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY
Editorial:
ELSEVIER SCIENCE BV
Referencias:
Lugar: Amsterdam; Año: 2016 vol. 45 p. 41 - 44
ISSN:
1382-6689
Resumen:
The current work evaluated the inhibitory potency of the herbicide glyphosate (GLP) on acetylcholinesterase (AChE) activity in male and female rat tissues. The AChE activity in brain was higher (p< 0.05) than those observed in kidney (females: 2.2-fold; males: 1.9-fold), liver (females: 6-fold; males: 6.9-fold) and plasma (females: 14.7-fold; males: 25.3-fold). Enzyme activities were higher in presence of 10 mM GLP compared to those measured at an equimolar concentration of the potent AChE inhibitor dichlorvos (DDVP). Moreover, ...
