IQUIBICEN 23947
INSTITUTO DE QUIMICA BIOLOGICA DE LA FACULTAD DE CIENCIAS EXACTAS Y NATURALES
Unidad Ejecutora - UE
congresos y reuniones científicas
Título:
Role of Prostaglandin E2 during the human immune response against Mycobacterium tuberculosis
Autor/es:
V. E. GARCIA; N. CASCO; MA. PAULA MORELLI; J. M. PELLEGRINI; D. J. PALMERO; ALBERTO LEVI; FLORENCIA CASTELLO; N. AMIANO; A. ROLANDELLI; N. L. TATEOSIAN
Lugar:
Buenos Aires
Reunión:
Congreso; Reunion Conjunta de Sociedades de Biociencias; 2017
Institución organizadora:
Sociedades Argentinas de Biociencias
Resumen:
Autophagy constitutes a direct mechanism of bacterial elimination and can be modulated by cytokines and other immunological mediators. PGE2, a bioactive lipid mediator derived from arachidonic acid, participates inthe initiation and resolution of inflammation and aids in the return to homeostasis.The aim of this work was to investigate whether PGE2 regulates the autophagy process and its role during the immune response of the host against Mycobacterium tuberculosis.
