IQUIBICEN 23947
INSTITUTO DE QUIMICA BIOLOGICA DE LA FACULTAD DE CIENCIAS EXACTAS Y NATURALES
Unidad Ejecutora - UE
congresos y reuniones científicas
Título:
Hemin treatment potentiates CD8+ T cell proliferation and effector function and impacts upon in vivo prostate cancer progression
Autor/es:
JAWORSKI, FELIPE; GENTILINI, LUCAS; GUERON, GERALDINE; COMPAGNO, DANIEL G.; VAZQUES, ELBA; LADERACH, DIEGO
Reunión:
Congreso; Congreso de la Sociedad Argentina de Inmunología; 2015
Institución organizadora:
Sociedad Argentina de Inmunología
Resumen:
Inflammatory microenvironments have been increasingly recognised as a risk factor for prostate cancer(PCa) and, in this regard, we have previously shown that modulation of inflammation-induced HemeOxygenase-1 (HO-1) profoundly impacts different aspects of disease progression. The present work focuseson the role of stromal HO-1. Subcutaneous TRAMP-C1 (TC1) tumours growing in syngeneic C57BL/6 micedisplayed increased tumour latency (12 days; P
