IQUIBICEN 23947
INSTITUTO DE QUIMICA BIOLOGICA DE LA FACULTAD DE CIENCIAS EXACTAS Y NATURALES
Unidad Ejecutora - UE
congresos y reuniones científicas
Título:
Mycobacterium tuberculosis LATENCY ANTIGENS MODULATE MONOCYTES FUNCTION FROM INFECTED INDIVIDUALS. "
Autor/es:
CASTELLO, FA; TATEOSIAN, NANCY; AMIANO, N; HERNANDEZ DEL PINO, R; PELLEGRINI, J; ROLANDELLI, A; GUTIERRES, M; PALMERO, D; GARCIA, V
Reunión:
Congreso; 1 Meeting LASID FAIC SAI; 2015
Resumen:
Our main aim is to investigate whether M. tuberculosis (Mtb)latency antigens regulate antigen presenting cell (APC)functions. Therefore, our specific objectives were:To analyze if Rv2626c and HspX antigens modulate the expression ofthe receptors TIM-3, PD-L1 and MHC class I on APCs from healthydonors (HD), subjects latently infected with Mtb (LTBI) andtuberculosis patients (TB).To investigate the effect of Rv2626c and HspX antigens on theproduction of cytokines by APCs from HD, TB and LTB
