Interactions of Aluminum with Erythroid Cells

VITTORI, D; VOTA, D; NESSE, A

Molecular and Supramolecular Bioinorganic Chemistry. Applications in Medical and Environmental Sciences. Volume 4

Nova Science Publishers, Inc.

Año: 2014; p. 91 - 112

Aluminum (Al) is a widespread element used extensively in contemporary life, but despite its ubiquity, no essential role has been demonstrated for this metal in biological systems. It is not surprising, then, that this nonessential metal was long considered harmless to humans [Sorenson et al., 1974]. The finding of a link between bone and neurological diseases in patients with renal failure under dialysis treatment and Al toxicity changed this belief. Nowadays, plenty of information suggests that, under certain environmental conditions, Al becomes toxic to plants, animals and humans. Further effort focused on this area will almost certainly improve our understanding of the influence of Al on biological systems.