Biochemical responses of the golden mussel Limnoperna fortunei under dietary glyphosate exposure.

SEBASTIÁN EDUARDO SABATINI; CATALDO DANIEL HUGO; MARÍA MERCEDES IUMMATO; MARÍA MERCEDES IUMMATO; ADRIANA CRISTINA COCHÓN; ADRIANA CRISTINA COCHÓN; ÁNGELA BEATRIZ JUÁREZ; ÁNGELA BEATRIZ JUÁREZ; LUIS CLAUDIO CACCIATORE; MARÍA DEL CARMEN RÍOS DE MOLINA; LUIS CLAUDIO CACCIATORE; MARÍA DEL CARMEN RÍOS DE MOLINA; SEBASTIÁN EDUARDO SABATINI; CATALDO DANIEL HUGO

ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

ACADEMIC PRESS INC ELSEVIER SCIENCE

Lugar: Amsterdam; Año: 2018 vol. 162 p. 69 - 75

0147-6513

The aim of this study was to analyze the biochemical alterations in the golden mussel Limnoperna fortunei underdietary glyphosate exposure. Mussels were fed during 4 weeks with the green algae Scenedesmus vacuolatuspreviously exposed to a commercial formulation of glyphosate (6 mg L−1 active principle) with the addition ofalkyl aryl polyglycol ether surfactant. After 1, 7, 14, 21 and 28 days of dietary exposure, glutathione-S-transferase(GST), catalase (CAT), superoxide dismutase (SOD), acetylcholinesterase (AChE), carboxylesterases (CES)and alkaline phosphatase (ALP) activities, glutathione (GSH) content and damage to lipids and proteins levelswere analyzed. A significant increase (72%) in the GST activity and a significant decrease (26%) in the CESactivity in the mussels fed on glyphosate exposed algae for 28 days were observed. The ALP activity was significantlyincreased at 21 and 28 days of dietary exposure (48% and 72%, respectively). GSH content and CAT,SOD and AchE activities did not show any differences between the exposed and non exposed bivalves. Nooxidative damage to lipids and proteins, measured as TBARS and carbonyl content respectively, was observed inresponse to glyphosate dietary exposure. The decrease in the CES activity and the increases in GST and ALPactivities observed in L. fortunei indicate that dietary exposure to glyphosate provokes metabolic alterations,related with detoxification mechanisms.