IQUIBICEN 23947
INSTITUTO DE QUIMICA BIOLOGICA DE LA FACULTAD DE CIENCIAS EXACTAS Y NATURALES
Unidad Ejecutora - UE
artículos
Título:
Detailing Protein Landscapes under Pressure
Autor/es:
ESPADA, ROCÍO; SÁNCHEZ, IGNACIO E.; FERREIRO, DIEGO U.
Revista:
BIOPHYSICAL JOURNAL
Editorial:
CELL PRESS
Referencias:
Año: 2016 vol. 111 p. 2339 - 2341
ISSN:
0006-3495
Resumen:
Natural protein molecules are remarkable physical objects. Despite the astronomical number of competing structural forms, these systems self-organize into beautiful structural ensembles in biologically short timescales, puzzling out the feat of specifically bringing together thousands of atoms interacting by a myriad of weak forces. Moreover, most protein domains appear to fold with ease in a deceptively simple twostate manner, populating either the fully folded or fully unfolded ensembles. This is certainly not a property of random amino acid chains.how do proteins do it?
