Enhanced analytical performance of paper microfluidic devices by using Fe3O4 nanoparticles, MWCNT and graphene oxide

FIGEREDO, FEDERICO; COLTRO, WENDELL K.T.; CORTÓN, EDUARDO; GARCIA, PAULO P

ACS APPLIED MATERIALS & INTERFACES

AMER CHEMICAL SOC

Lugar: Washington; Año: 2016 vol. 8 p. 11 - 15

1944-8244

Spheres, tubes and planar shaped nanomaterials as Fe3O4 nanoparticles (MNPs), multi walled carbon nanotubes (MWCNT) and graphene oxide (GO) were used for the first time to treat microfluidic paper-based analytical devices (μPADs) and create a biocompatible layer with high catalytic surface. The analytical performance was studied by using bi-enzymatic colorimetric detection of glucose. The limit of detection values achieved for glucose with μPADs treated with MNPs, MWCNT and GO were 43, 62 and 18 μM, respectively. The paper surface modification solves problems associated with the lack of homogeneity on color measurements that compromise the sensitivity and detectability levels in clinical diagnosis.