IQUIBICEN   23947
INSTITUTO DE QUIMICA BIOLOGICA DE LA FACULTAD DE CIENCIAS EXACTAS Y NATURALES
Unidad Ejecutora - UE
artículos
Título:
Regulation of Transcription Factors by Tumor-Specific MAGE Proteins
Autor/es:
LAISECA, JE; PASCUCCI, F; MONTE, M; LADELFA MF
Revista:
Journal of Biochemistry and Molecular Biology Research
Editorial:
Act Publising
Referencias:
Año: 2015 vol. 1 p. 112 - 117
Resumen:
The tumor specific melanoma antigen gene (MAGE-I) family was initially considered promising and selective targets for immunotherapy. Currently, their functional characterization points to a role in transcription regulation. In this article we focus on Mage-A proteins as regulators of transcription factors involved in different cancer-related pathways and how this regulation could contribute to tumorigenesis.