IQUIBICEN   23947
INSTITUTO DE QUIMICA BIOLOGICA DE LA FACULTAD DE CIENCIAS EXACTAS Y NATURALES
Unidad Ejecutora - UE
artículos
Título:
Delineating the galectin signature of the tumor microenvironment
Autor/es:
COMPAGNO DANIEL; LADERACH DIEGO; GENTILINI, LUCAS; JAWORSKI FELIPE ; RABINOVICH, GABRIEL
Revista:
oncoimmunology
Editorial:
Landes Bioscience Journal
Referencias:
Año: 2013 vol. 2 p. 235651 - 235653
ISSN:
2162-402x
Resumen:
Galectins, a family of glycan-binding proteins, can control tumor progression by promoting transformation, angiogenesis and immune escape. We identified a dynamically regulated ‘galectin signature’, which delineates the progression of prostate cancer, highlighting galectin-1 as an attractive target for anti-angiogenic therapy in advanced stages of the disease.