Antiparasitic efficacy of a Ricobendazole controlled release formulation against Ancylostoma caninum and Trichuris sp intended for oral administration in dogs

ALDROVANI A; PALMA S. D; ALEJANDRO PAREDES; DIB A; LANUSSE , C; ALLEMANDI D,; SANCHEZ BRUNI, S;

Veterinaria (Montevideo)

Sociedad de Medicina Veterinaria del Uruguay

Lugar: Montevideo; Año: 2016 vol. 52 p. 11 - 21

0376-4362

The aim of this work was to evaluate the clinical oral efficacy in dogs of two different single doses (20 mg/kg and 10 mg/kg) of a controlled release (CR) Ricobendazole (RBZ) based formulation formulated within a lipid matrix of CetylAlcohol and compare it with those of one single dose RBZ immediate release (IR) formulation (20 mg/kg) and one Albendazole (ABZ) IR formulation (25 mg/kg)(3 consecutive doses q/24 h). Thirty naturally parasitised dogs with Ancylostomacaninum and Trichuris sp were randomly allocated to five groups (n=6). A pair-sample t- Test (p