Body mass index and human sperm quality: Neither one extreme nor the other.

LUQUE E; MOLINA RI; BELTRAMONE F; FIOL DE CUNEO M; TISSERA A; MANGEAUD A; SAD J; GAGGINO MP; MARTINI AC; VINCENTI LM; ESTOFÁN D

REPRODUCTION FERTILITY AND DEVELOPMENT

CSIRO PUBLISHING

Lugar: Collingwood; Año: 2017 vol. 29 p. 731 - 739

1031-3613

Purpose: To study the still controversial association between BMI and seminal quality.Methods: This study included 4860 patients (non-smokers or drinkers), classified according to their body mass index (BMI) as: underweighted (UW)=BMI40, n=57. Conventional semen parameters and seminal concentrations of fructose, citric acid and neutral alpha-glucosidase (NAG) were studied.Results: Low weight and morbid obesity significantly decreased sperm concentration and total count (MOB=121.5±20.6 and UW=157.9±3.6 vs NW=157.9±3.6, OW=152.4±2.7 or OB=142.1±4.3), motility (MOB=42.6±2.6 and UW=41.8±2.5 vs NW=47.8±0.5, OW=48.0±0.4 or OB=46.3±0.6) and NAG (MOB=60.1±7.9 and UW=45.2±6.6 vs NW=71.5±1.9, OW=64.7±1.3 or OB=63.1±2.1); these parameters reflect epididymal maturation. Moreover, MOB patients showed a decrease in the percentage of morphologically normal spermatozoa (MOB=4.8±0.6 vs UW=6.0±0.8, NW=6.9±0.1, OW=6.8±0.1 or OB=6.4±0.2; p