INICSA 23916
INSTITUTO DE INVESTIGACIONES EN CIENCIAS DE LA SALUD
Unidad Ejecutora - UE
artículos
Título:
Effects of dietary omega-3 PUFAs on growth and development: Somatic, neurobiological and reproductive functions in a murine model
Autor/es:
BIANCONI, SANTIAGO; MARTINI, ANA C.; SCHIÖTH, HELGI B.; SANTILLÁN, MARÍA E.; SOLÍS, MARÍA DEL ROSARIO; PONZIO, MARINA F.; VINCENTI, LAURA M.; CARLINI, VALERIA P.; STUTZ, GRACIELA
Revista:
JOURNAL OF NUTRITIONAL BIOCHEMISTRY
Editorial:
ELSEVIER SCIENCE INC
Referencias:
Año: 2018 vol. 61 p. 82 - 90
ISSN:
0955-2863
Resumen:
Omega-3 polyunsaturated fatty acids (ω-3 PUFAs) are relevant to fetal and infant growth and development. Objective: to assess whether long-term exposure to dietary ω-3 PUFA imbalance alters pre- and/or postnatal pups´ development and reproductive function later in life. Mice dams were fed with ω-3 PUFA Control (soybean oil, 7%), Deficient (sunflower oil, 7%) or Excess (blend oil; 4.2% cod-liver+2.8% soybean) diet before conception and throughout gestation-lactation and later on, their pups received the same diet from weaning to adulthood. Offspring somatic, neurobiological and reproductive parameters were evaluated. Excess pups were lighter during the preweaning period and shorter in length from postnatal day (PND) 7 to 49, compared to Control pups (P
