INSTITUTO DE DIVERSIDAD Y ECOLOGIA ANIMAL
Unidad Ejecutora - UE
Occurrence and bioaccumulation of pharmaceuticals in a fish species inhabiting the Suquía River basin (Córdoba, Argentina)
VALDES, MARIA EUGENIA; AMÉ, MARÍA VALERIA; BISTONI, M A; WUNDERLIN, DANIEL ALBERTO
SCIENCE OF THE TOTAL ENVIRONMENT
ELSEVIER SCIENCE BV
Lugar: Amsterdam; Año: 2014 vol. 472 p. 389 - 389
In SouthAmerica, there is a lack of data concerning the occurrence and levels of pharmaceuticals inmain rivers as well as their negative effects on the biota. Here we report the occurrence as well as the spatial and temporal variations of some common prescribed pharmaceuticals in the Suquía River basin (Córdoba, Argentina). We also report the bioconcentration of two of them in Gambusia affinis, a widely distributed fish species inhabiting the river basin. The influence of the wastewater treatment plant of Córdoba Citywas critical (up to 70 km downstream). Among 15 compounds analyzed, atenolol, carbamazepine and diclofenac were the most frequently detected (reaching sub μg L−1 levels), showing different distribution patterns. Bioconcentration of atenolol and carbamazepine was studied under laboratory controlled conditions. Estimated bioconcentration factors (BCFs) were: 0.13 and 0.08 L kg−1 upon exposure to 100 and 1000 μg L−1 atenolol in water, respectively; while BCFs were 0.7 and 0.9 L kg−1 when exposed to 10 and 100 μg L−1 carbamazepine, respectively. To the extent of our knowledge, this is the first report on pharmaceuticals in superficial waters of Argentina as well as the firstreport on the bioaccumulation of atenolol in whole body fish.