Essential oil of Tagetes filifolia against the flour beetle Tribolium castaneum and its relation to acetylcholinesterase activity and lipid peroxidation

OLMEDO R. H.; HERRERA J. M.; LUCINI, E.; ZUNINO, M.; PIZZOLITTO J. S.; DAMBOLENA SEBASTIAN; ZYGADLO, J.

agriscientia

Universidad Nacional de Córdoba

Lugar: Córdoba; Año: 2015 vol. 32 p. 113 - 121

The development of natural insecticides would help to decrease the negative impact of synthetic insecticides. Fumigant toxicity of essential oil of Tagetes flifolia Lag (Asterales: Asteraceae) and its major compounds were evaluated against essential oils were analyzed by gas chromatography?mass spectrometry. The essential oil and (E)-anethole were the most toxic at 24 h against adult insects (CL = 2.4 y 2.6 µL/mL water, respectively). Changes in the products of lipid peroxidation were evidenced by an increase in malondialdehyde content. Acetylcholinesterase activity in vitro, of T. castaneum adults, was also reported. (E)-anethole and estragole showed similar acetylcholinesterase inhibition (54 and 63%, respectively at 5 mM). The present study constitutes one of the frst contributions to understanding the relationship between the insecticidal action of essential oil and oxidative stress.