INVESTIGADORES
GIL Jose Fernando
congresos y reuniones científicas
Título:
ANALYSIS OF JOINT VARIATION BETWEEN HUMAN CASES OF TEGUMENTARY LEISHMANIASIS AND SAND FLY ABUNDANCE IN A HYPER?ENDEMIC AREA OF ARGENTINA.
Autor/es:
ALMAZAN, MC; COPA, GN; GIL, JF; LOPEZ QUIROGA, I; HOYOS, CL; CAJAL, SP; DIAZ FERNANDEZ, ME; NASSER, JR; KROLEWIECKI, AJ; CIMINO, RO; MARCO, JD; BARROSO, P
Lugar:
Mar del Plata
Reunión:
Encuentro; XXXI Annual Meeting of Sociedad Argentina de Protozoología (SAP); 2019
Institución organizadora:
Sociedad Argentina de Protozoologia
Resumen:
Leishmaniases are a group of diseases caused by Leishmaniaparasites that are transmitted by sand fly female bite. In Argentina, the northof Salta province is a hyper-endemic area of Tegumentary Leishmaniasis (TL),being Oran department one of the most affected zones. To achieve deeper knowledgeabout the disease transmission in that region, we studied the joint variationof TL cases and sand fly abundance in two periurban sites of Oran. Sand flycaptures were executed with CDC traps placed at the neighborhoods El Cedral(EC) (one night/sampling) and Taranto (TA) (three nights/sampling) across ayear. Species identification of female sandflies was made by observation ofspermatheca and cibarium. Also, the clinical information of patients diagnosedat Instituto de Investigaciones de Enfermedades Tropicales (IIET) since 1989 to2018 was analyzed to determine the monthly mean of TL cases and the time ofevolution of lesions. A total of 102 female sandflies were caught in ECneighborhood, while 1,434 in TA. The most abundant species was Nyssomyianeivai. The months with the highest proportion of gravid females were Decemberand February for EC and TA neighborhoods, respectively (p<0.05). Regardingpatient information, the male: female ratio was 6:1 with a median age of 32years old. The time of evolution determined was one month. It was seen that thepeak of patient cases took place in March for EC and in May for TA neighborhoods,namely three months later. This lag between gravidness period (high risk ofinfection) and peaks of TL cases may be explained due to the time of evolution(one month), plus an incubation period that seems to last two months.Considering the sex ratio and the productive age of patients, the transmission couldhave been mainly sylvatic during work activities. The analysis of jointvariation allowed reaching a better characterization of disease transmissionwhich is fundamental for designing and implementing prevention and controlmeasures.