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We present a product formula for the initial parts of the sparse resultant associated to an arbitrary family of supports, generalizing a previous result by Sturmfels. This allows to compute the homogeneities and degrees of this sparse resultant, and its evaluation at systems of Laurent polynomials with smaller supports. We obtain an analogous product formula for some of the initial parts of the principal minors of the Sylvester-type square matrix associated to a mixed subdivision of apolytope.Applying these results, we prove that under suitable hypothesis, the sparse resultant can be computed as the quotient of the determinant of such a square matrix by one of its principal minors. This generalizes the classical Macaulay formula for the homogeneous resultant, and conrms a conjecture of Canny and Emiris.