Vitamin D Status/ Insufficiency May Predict Physical Performance in a Group of Osteopenic/Osteoporotic Women. Preliminary Study

MASTAGLIA SR, SEIJO M, MUZIO DM, OLIVERI B

Honolulu, Hawaii, USA

Congreso; Twenty- Ninght Annual Meeting of the American Society for Bone and Mineral Research; 2007

The American Society for Bone and Mineral Research

Hypovitaminosis D is frequent in population over 65 years of age, producing a secondary hyperparathyroidism, increase of bone remodeling, bone loss and osteoporotic fractures, loss of the muscle force function. The aim of this study was to assess the vitamin D (25OHD) nutritional state in osteopenic/osteoporotic women >65 and the relationship with muscle force and function. To date, forty women were assessed, with an average age (X¡ÀDS) 71.2¡À5.3, body mass index (BMI) 27.5¡À4.2, with a bone mineral density (BMD) ( DXA-LUNAR) of femoral neck (FN) 0.752¡À0.71 (T- 1.9). The exclusion criteria applied were: having received vitamin D during the year preceding the study, pathology or medication affecting mineral metabolism, neurological and/or motor-function disease. The physical performance of lower limbs (walking speed, balance, standing-up and sitting-down) and the hip force with a dynamometer was assessed. The population sample was divided into two groups, taking as cut point 20ng/ml of 25OHD (Lips P Endocr Rev 2001): Group 1 (G1): > 20 ng/ml, Group 2: (G2) ¡Ü 20 ng/ml. The results obtained are shown in the table.A lower score in the physical performance and a tendency to a lesser left hip abduction in women with 25OHD ¡Ü20ng/ml was observed.Preliminary data show that the levels of insufficient vitamin D could predict physical performance in osteopenic/osteoporotic women >65. Table 25OHD (ng/ml) Left Hip Flexion Left Hip Abduction Physical Performance G1 (n=20) 31.85¡À6.4 13.8¡À1.8 7.33¡À1.66 11.1 G2 (n=20) 12.9¡À3.9 14.01¡À2.4 6.74¡À2.09 9.6 p 0.000 NS 0.1>p>0.05 0.02