Cationic starch: A functionalized polysaccharide based polymer for advancement of drug delivery and health care system - A review

CHATTERJEE, SHREYA; MAHMOOD, SYED; HILLES, AYAH REBHI; THOMAS, SABU; ROY, SUDEEP; PROVAZNIK, VALENTINE; ROMERO, EDER LILIA; GHOSAL, KAJAL

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

ELSEVIER SCIENCE BV

Año: 2023 vol. 248

0141-8130

Research and development in health care industry is in persistence progression. To make it more patient-friendlyor to get maximum benefits from it, special attention to different advanced drug delivery system (ADDS) isemployed that delivers the drug at the target site and will be able to sustain/control release of drugs. ADDSshould be non-toxic, biodegradable, biocompatible along with desirable showing physicochemical and functionalproperties. These drug delivery systems can be totally based on polymers, either with natural or syntheticpolymers. The molecular weight of polymer can be tuned and different groups of polymers can be modified orsubstituted with other functional groups. Degree of substitution is also tailored. Cationic starch in recent years isexploited in drug delivery, tissue engineering and biomedicine. Due to their abundant availability, low cost, easychemical modification, low toxicity, biodegradability and biocompatibility, extensive research is now beingcarried out. Our present discussion will shed light on the usage of cationic starch in health care system