INVESTIGADORES
VINDEROLA Celso Gabriel
artículos
Título:
Spray-drying process preserves the protective capacity of a breast milk-derived Bifidobacterium lactis strain on acute and chronic colitis in mice
Autor/es:
BURNS, P; ALARD, J; HRDY, J.; BOUTILLIER, D; POT, B; PÁEZ, R; REINHEIMER, J.; C.G. VINDEROLA; GRANGETTE, C.
Revista:
Scientific Reports
Editorial:
Nature
Referencias:
Año: 2017 vol. 7
Resumen:
Gut microbiota dysbiosis plays a central role in the development and perpetuation of chronicinflammation in inflammatory bowel disease (IBD) and therefore is key target for interventions withhigh quality and functional probiotics. The local production of stable probiotic formulations at limitedcost is considered an advantage as it reduces transportation cost and time, thereby increasing theeffective period at the consumer side. In the present study, we compared the anti-inflammatorycapacities of the Bifidobacterium animalis subsp. lactis (B. lactis) INL1, a probiotic strain isolated inArgentina from human breast milk, with the commercial strain B. animalis subsp. lactis BB12. Theimpact of spray-drying, a low-cost alternative of bacterial dehydration, on the functionality of bothbifidobacteria was also investigated. We showed for both bacteria that the spray-drying process did notimpact on bacterial survival nor on their protective capacities against acute and chronic colitis in mice,opening future perspectives for the use of strain INL1 in populations with IBD.