RNA-mediated virus resistance.

VAZQUEZ-ROVERE CECILIA; DEL VAS, M; HOPP, H.E

CURRENT OPINION IN BIOTECHNOLOGY

Elsevier

Lugar: Paises Bajos; Año: 2002 vol. 13 p. 167 - 172

0958-1669

Post-transcriptional gene silencing is an RNA degradation mechanism that can be induced by viruses. Recent evidence indicates that silencing may also be involved in virus synergism, tissue limitation of virus spread, non-host resistance, virus transmission through seeds and in more general mechanisms of defense such as that mediated by salicylic acid. The analysis of Arabidopsis mutants, and of viruses carrying silencing suppressors, has led to a greater understanding of posttranscriptional gene silencing pathways. Much still remains to be discovered, however, not least to allow the successful exploitation of gene silencing in conferring pathogen resistance to transgenic plants.Arabidopsis mutants, and of viruses carrying silencing suppressors, has led to a greater understanding of posttranscriptional gene silencing pathways. Much still remains to be discovered, however, not least to allow the successful exploitation of gene silencing in conferring pathogen resistance to transgenic plants.