VARIATIONS ON PANCREATIC SECRETION DUE TO DIFFERENT CONCENTRATIONS OF DIETARY FAT IN RATS.

SABBATINI M; RIOS M; BIANCIOTTI LG; VATTA MS

CIUDAD AUTONOMA DE BUENOS AIRES-ARGENTINA

Congreso; INTERNACIONAL ADVANCES IN THE CARE AND USE OF LABORATORY ANIMALS; 2004

ASOCIACION ARGENTINA PARA LA CIENCIAS Y TECNOLOGIA DE LOS ANIMALES DE LABORATORIO

The aim of the present work was to determine the importance of dietary fat present in animal commercial chow on pancreatic function. For these studies two different commercial chows were chosen. Sprague-Dawley rats were randomly divided into two groups. One group was fed with a diet containing 4.0% of fat whereas the other group was fed with a diet containing 2.9% of fat (ISO/IRAM standards). Animals fed with commercial chow containing 4.0% of fat exhibited higher pancreatic flow as compared with the animals that received a commercial chow containing 2.9% fat. In addition, the pancreatic flow generated by rats fed with the diet containing 2.9% fat was too small to allow measurement of pancreatic components. Present results show that the percentage of fat present in a particular diet is very important to evoke a normal pancreatic secretion. Further these results strongly support that commercial chows should fulfill the recommended requirements (above 3%) as regards fat percentage to avoid alterations in physiological functions.