Modulation of Piriform Cortex Neuronal Activity by Inputs from Basolateral Amygdala and Lateral Entorhinal Cortex

OLIVIA PEDRONCINI; NOEL FEDERMAN; ANTONIA MARIN BURGIN

Cordoba

Congreso; san 2018; 2018

SAN

Piriform cortex is the main region of the olfactory cortex where olfactory information is encoded. It receives sensory afferences from the olfactory bulb but also from other higher order brain regions such as the entorhinal cortex and the amygdala. Here we study how the basolateral amygdala (BLA) and the lateral entorhinal cortex (LEC) are functionally connected to the posterior piriform cortex (pPC) and how these inputs modulate neuronal activity of the circuit. Deciphering the interaction between sensory ?bottom-up? and ?top-down? projections from higher brain areas will shed light on the understanding of how the brain could adaptively shape sensory cortical activity according to behavioral needs.