Modulation of Piriform Cortex Neuronal Activity by Inputs from Basolateral Amygdala and Lateral Entorhinal

ANTONIA MARIN BURGIN; NOEL FEDERMAN; OLIVIA PEDRONCINI

buenos aires

Congreso; Frontiers in Bioscience 2018; 2018

IBioBA-MPSP | Instituto Max Planck Argentina

Piriform cortex is the main region of the olfactory cortex where olfactory information is encoded. It receives sensory aferences from the olfactory bulb but also from other higher order brain regions such as the entorhinal cortex and the amygdala. Here we study how the basolateral amygdala (BLA) and the lateral entorhinal cortex (LEC) are functionally connected to the posterior piriform cortex (pPC) and how these inputs modulate neu-ronal activity of the circuit. Decipher-ing the interaction between sensory ?bottom-up? and ?top-down? projec-tions from higher brain areas will shed light on the understanding of how the brain could adaptively shape sensory cortical activity according to behav-ioral needs.