IBAM 22618
INSTITUTO DE BIOLOGIA AGRICOLA DE MENDOZA
Unidad Ejecutora - UE
artículos
Título:
Chemometric and green metric strategies for sustainable analytical methods: phenolic compounds in lettuce-NADES extracts
Autor/es:
PASINI, SERGIO; CANALES, ROMINA; SILVA, MARÍA FERNANDA; ESPINO, MAGDALENA
Revista:
Analytical Methods
Editorial:
The Royal Society of Chemistry
Referencias:
Año: 2021 vol. 13 p. 1261 - 1268
ISSN:
1759-9660
Resumen:
The combination of chemometric and green metric tools adds up to synergistic effects at methoddevelopment, being highly compatible with green analytical chemistry (GAC). In the present study, bothstrategies were applied for the development of an ultrasound-assisted extraction mediated by NaturalDeep Eutectic Solvent (UA-NADES). The Box?Behnken Design combined with multiple responses anddesirability functions allowed the effective optimization of the proposed extractive methodology usingan alternative green solvent. Considering the obtained results, a green UA-NADES extraction andchromatographic determination of phenolic compounds in Lactuca sativa samples were developed.Finally, the recent Analytical GREEnness metric approach was applied, and scores were compared withrecent miniaturized approaches for the extraction/determination of phenolic compounds in lettuce. The results of the AGREE analysis highlight the greenness of the proposed methodology
