INVESTIGADORES
RABINOVICH Gabriel Adrian
artículos
Título:
THWARTING GALECTIN-INDUCED IMMUNOSUPPRESSION IN BREAST CANCER
Autor/es:
MARIANA SALATINO; TOMAS DALOTTO; GABRIEL RABINOVICH
Revista:
ONCOIMMUNOLOGY
Editorial:
Landes Biosciences
Referencias:
Lugar: Paris; Año: 2013 vol. 2 p. 24077 - 24079
ISSN:
2162-4011
Resumen:
Novel therapeutic strategies are needed to counteract breast cancer-associated immunosuppression. Silencing the expression of galectin-1 in a breast carcinoma model inhibited tumor growth and prevented lung metastasis by reducing the frequency and immunosuppressive activity of CD4+CD25+ FOXP3+ regulatory T cells.
