INVESTIGADORES
RABINOVICH Gabriel Adrian
artículos
Título:
DELINEATING THE GALECTIN SIGNATURE OF THE TUMOR MICROENVIRONMENT
Autor/es:
DANIEL COMPAGNO; DIEGO LADERACH; LUCAS GENTILINI; FELIPE JAROWSKI; GABRIEL RABINOVICH
Revista:
ONCOIMMUNOLOGY
Editorial:
LANDES BIOSCIENCE
Referencias:
Lugar: PARIS; Año: 2013 vol. 2
ISSN:
2162-4011
Resumen:
Galectins, a family of glycan-binding proteins, can control tumor progression by promoting tumor transformation, angiogenesis and immune escape. We identified a dynamically regulated ?galectin-specific signature? which delineates prostate cancer progression, highlighting a major role for galectin-1 as an attractive target for anti-angiogenic therapy in advanced stages of the disease.