INVESTIGADORES
OGGERO EBERHARDT Marcos Rafael
artículos
Título:
Chemistry of polyhalogenated nitrobutadienes, 19: Synthesis of new types of compound modulating the biological activity of Type I Interferons (IFN-I)
Autor/es:
ZAPOLSKII, VIKTOR; BURGI, MARÍA DE LOS MILAGROS; OGGERO MARCOS; BOLLATI-FOGOLÍN, MARIELA; KAUFMANN, DIETER
Revista:
ARKIVOC - ONLINE JOURNAL OF ORGANIC CHEMISTRY
Editorial:
ARKAT USA INC
Referencias:
Lugar: Florida; Año: 2023
ISSN:
1551-7004
Resumen:
The synthesis of ten new types of compound derived from polyhalonitroalkenes is described starting from the versatile solvent trichloroethene. The new compounds modulate the biological activity of Type I Interferons (IFN-I). Three of them (bornylamine derivative P6C11, chlorothiophene P28G6, and nitroindole P28F7) are promising candidates to inhibit rhIFN activity.
