MIRANDA Leandro Andres
Effects of heavy metals identified in Chascomús shallow lake on the endocrine-reproductive axis of pejerrey fish (Odontesthes bonariensis)
GÁRRIZ A; DEL FRESNO PS; CARRIQUIRIBORDE P; MIRANDA LA
GENERAL AND COMPARATIVE ENDOCRINOLOGY
ACADEMIC PRESS INC ELSEVIER SCIENCE
Lugar: Amsterdam; Año: 2019 vol. 273 p. 152 - 152
some heavy metals related to human activities were measured in the water of Chascomús lake. The maximumconcentrations were: 0.23 μg/L for Cd, 4.28 μg/L for Cr, 22.09 μg/L for Cu, 2.49 μg/L for Ni, 3.24 μg/L for Pb and210.76 μg/L for Zn. The values of Cd, Cr, Cr, Pb and Zn were above the Argentine National Guidelines for theProtection of the Aquatic life. The analysis of gonadal condition of pejerrey fish (Odontesthes bonariensis) fromthis lake did not revealed any reproductive damages. However, exposures with environmental concentrations ofCd, Cr, Cu and Zn under laboratory conditions of pejerrey males (14 days), caused a significant increase of theexpression of the three variants of gnrh in the brain (within Cd exposure) and a decrease in cyp19a1b mRNA(within Cu exposure). Furthermore, at pituitary level, a decrease in fshb transcript levels was observed in the fishexposed to Cd and Cr and a decrease in the expression of both gonadotropin receptors at gonadal level in Znexposure. Moreover, the gonads of the fish exposed to all the tested metals suffered structural damages showingshortness of the spermatic lobules, fibrosis, testis ova and the presence of piknotic cells. All these findings alertthat heavy metals pollution affects the expression of key reproductive genes and gonadal structure of fish speciesthat represent the predominant group of organisms and are considered sentinel species in the aquatic ecosystems.