INVESTIGADORES
MATHET Veronica Lidia
artículos
Título:
A comprehensive bioinformatic analysis of hepatitis D virus (HDV) full-length genomes
Autor/es:
DELFINO CM; CERRUDO C; BIGLIONE M; OUBIÑA J; GHIRINGHELLI P; MATHET V.
Revista:
JOURNAL OF VIRAL HEPATITIS.
Editorial:
WILEY-BLACKWELL PUBLISHING, INC
Referencias:
Lugar: Londres; Año: 2018
ISSN:
1352-0504
Resumen:
In association with hepatitis B virus (HBV), hepatitis delta virus (HDV) is a subviral agentthat may promote severe acute and chronic forms of liver disease. Based on the percentage ofnucleotide identity of the genome, HDV was initially classified into three genotypes.However, since 2006, the original classification has been further expanded into eightclades/genotypes. The intergenotype divergence may be as high as 35-40% over the entireRNA genome, whereas sequence heterogeneity among the isolates of a given genotype is